F-75 milk - initial phase of SAM treatment (or stabilization phase), according to the WHO protocol
400 g tin (enriched powdered milk to be reconstituted)
✓ Treatment of medical problems, correction of specific deficiencies, correction of metabolic abnormalities, return of appetite and start of feeding (medical supervision)
For any case of SAM with medical complication and/or without appetite
130 ml of reconstituted milk / kg / day
→ 80-100 kcal / kg / day divided into 8 to 12 meals / day for 3 to 7 days
F-75 is a therapeutic milk powder
✓ For any case of severate acute malnutrition with medical complication and/or without appetite
When a child suffering from severe acute malnutrition arrives at the hospital, he/she often shows infections, hepatic and intestinal insufficiency, or electrolyte imbalances (excess or insufficiency of elements such as sodium, potassium, calcium or even magnesium). A child with such complications is unable to tolerate usual levels of proteins, fats and sodium. Therefore, it is important to begin nutritional treatment by giving foods with low levels of proteins, fats and sodium, but rich in carbohydrates.
F-75 therapeutic milk should be used in therapeutic feeding centers under medical supervision, and must never be given directly to families.
✓ To treat Severe Acute Malnutrition - Phase 1
F-75 therapeutic milk was designed for the stabilisation phase of inpatients suffering from severe acute malnutrition, that is phase 1 of the treatment protocol drawn up by the World Health Organisation (WHO). That stabilisation phase consists in ensuring the rehydration of children and the treatment of their medical complications, while initiating refeeding.
With its caloric density of 75 kcal per 100 ml of reconstituted milk, F-75 is not intended to make children put on weight, and its use should be limited to phase 1 (on average, 3 days).
>>> In phase 2, the nutritional recovery phase, F-100 therapeutic milk is used (or a ready-to-use nutritional equivalent such as Plumpy’Nut®, depending on the child's state of health).
F-75 therapeutic milk is not adapted for well-nourished children
Immediate breastfeeding after birth, exclusive during the first 6 months and recommended for at least 24 months.
Main nutritional values
|F-75 therapeutic milk formula: elements for 100 ml of F-75 reconstituted milk*|
|Energy||77 kcal||Copper||0.27 mg||Vitamin B1||> 85 µg|
|Proteins (% of the total energy)||5%||Iron||< 0.06 mg||Vitamin B2||> 0.3 mg|
|Lipids (% of the total energy)||29.9%||Iodine||17.9 µg||Vitamin B6||> 0.1 mg|
|65%||Selenium||5.1 µg||Vitamin B12||> 0.3 µg|
|Calcium||77 mg||Sodium||< 17 mg||Vitamin K||2.6-8.2 µg|
|Phosphorus||77 mg||Vitamin A||0.14-0.3 mg||Biotin||> 10 µg|
|Potassium||142 mg||Vitamin D||2.6-4.9 µg||Folic acid||> 34 µg|
|Magnesium||9.5 mg||Vitamin E||3.4-4.9 mg||Pantothenic acid||> 0.51 mg|
|Zinc||2.5 mg||Vitamin C||> 8.5 mg||Niacin||> 0.85 mg|
*The values given in this table are based on Nutriset's knowledge of the intrinsic nutrient content of the raw materials and their variability, as well as the variability of the process.
Lanyero B. et al. Transition from F-75 to ready-to-use therapeutic food in children with severe acute malnutrition, an observational study in Uganda. Nutr J. 2017 Aug 30;16(1):52.
Bhutta ZA et al.. Severe childhood malnutrition. Nat Rev Dis Primers. 2017 Sep 21;3:17067.
Versloot CJ1 et al. Effectiveness of three commonly used transition phase diets in the inpatient management of children with severe acute malnutrition: a pilot randomized controlled trial in Malawi. BMC Pediatr. 2017 Apr 26;17(1):112.
Rytter MJ. Risk factors for death in children during inpatient treatment of severe acute malnutrition: a prospective cohort study. Am J Clin Nutr. 2017 Feb;105(2):494-502.
Namusoke H. et al. Changes in plasma phosphate during in-patient treatment of children with severe acute malnutrition: an observational study in Uganda. Am J Clin Nutr. 2016 Feb;103(2):551-8.
WHO, Management of severe malnutrition: a manual for physicians and other senior health workers. 1999
Golden MHN Severe malnutrition. In: Weatherall DJ, Ledingham JGG, Warell DA eds The Oxford Textbook of Medicine. Oxford: Oxford University Press Vol1 3rd edition 1995; 1278-1296