Ready-to-Use Supplementary Food (RUSF) - Lipid-based Nutrient Supplement (LNS)
100 g individual sachet [545 kcal]
✓ Nutritional support for HIV+ adults under antiretroviral therapy
2 sachets / day / adult
→ Covers the increased needs in the main vitamins and minerals and provides 1 090 kcal and 44 g of proteins.
Plumpy’ART™ is a Ready-to-Use Supplementary Food (RUSF) also defined as a Lipid-based Nutrient Supplement (LNS)
✓ For adults
Plumpy’ART™ is a Ready-to-Use Food designed to supplement HIV+ adults under antiretroviral therapy whose daily food ration does not provide the recommended amounts of macronutrients and micronutrients.
Plumpy’ART™ is not substitute for a varied and nutritious diet.
Main nutritional values
|Plumpy’ART™ formula: elements for 100 g*|
|Energy||545 kcal||Selenium||26 µg||Vitamin B12||2,4 µg|
|Proteins||22 g||Manganese||0,5mg||Vitamin K||5,5 mg|
|Lipids||36,5 g||Vitamin A||0,5mg||Biotin||30 µg|
|Calcium||500 mg||Vitamin D||5 µg||Folic Acid||400 µg|
|Magnesium||110 mg||Vitamin E||7,5 mg||Pantothenic acid||5 mg|
|Zinc||3 mg||Vitamin C||50 mg||Niacin||14mg|
|Copper||1,5 mg||Vitamin B1||1,1 mg|
|Iron||4,5 mg||Vitamin B2||1,1 mg|
|Iodine||55 µg||Vitamin B6||1,3 mg|
*The values given in this table are based on Nutriset's knowledge of the intrinsic nutrient content of the raw materials and their variability, as well as the variability of the process. Values may vary.
Clinical trials investigating the role of micronutrient and macronutrient supplementation in relation to Antiretroviral treatment (ART) of HIV patients
Several clinical trials have investigated the role of micronutrient and macronutrient supplementation on HIV-related treatment outcomes:
- Lancet HIV: RUSF impact has been tested on HIV patients starting ART. Afters 24 weeks these immunocompromised patients receiving a RUSF in clinics in Kenya, Malawi, Uganda and Zimbabwe had greater gains of weight, BMI and mid-upper arm circumference versus the control group.
- ARTfood: this trial in Ethiopia highlighted the fact that at the start of ART a 3-months’ lipid based nutrient supplementation was leading to a gain in weight, lean body mass and grip strength.
- NUSTART: a significant increase in CD4 cell counts resulted from a supplementation in vitamins and minerals during a trial in Tanzania and Zambia.
- In Malawi under-nourished HIV patients starting ART supplemented with RUSF during 14 weeks showed increased weight and lean mass compared to the patients supplemented with Corn-Soy Blend (CSB).
In the light of these findings, several scientists emphasized that it is crucial to continue to encourage nutritional support for patients with HIV under ART because it may increase lean mass, hasten physical and functional recovery, and improve work capacity and quality of life.
Mallewa J et al. Effect of ready-to-use supplementary food on mortality in severely immunocompromised HIV-infected individuals in Africa initiating antiretroviral therapy (REALITY): an open-label, parallel-group, randomised controlled trial. Lancet HIV 2018; Volume 5, No. 5, e231–e240, May 2018.
Ndekha MJ et al. Supplementary feeding with either ready-to-use fortified spread or corn-soy blend in wasted adults starting antiretroviral therapy in Malawi: randomised, investigator blinded, controlled trial. BMJ 2009; 338: b1867.