Moderate acute malnutrition (treatment)

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Ready-to-use Supplementary Food (RUSF) - Lipid-based Nutrient Supplement Large Quantity (LNS-LQ)

100 g individual sachet [540 kcal]

✓ Treatment of moderate acute malnutrition

From 6 months 

About 75 kcal / kg / day during 2 months

→ 1 sachet / day / person

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Plumpy'Sup™ is a Ready-to-Use Supplementary Food (RUSF) also defined as a Lipid-based Nutrient Supplement Large Quantity (LNS-LQ)

 

For children after 6 months of age

In the first years of life, children living in developing countries are most at risk of undernutrition. As this is an important period of growth and development, it is crucial to correct the nutritional status of these young groups as early as possible.

Plumpy'Sup™ has been designed for the treatment of moderate acute malnutrition from the age of 6 months as part of nutritional supplementation programs. Plumpy'Sup ™ is also suitable for children who are coming out of therapeutic nutrition programs, to prevent relapse into severe acute malnutrition.

Plumpy’Sup should not be given to people who are allergic to peanuts, dairy products or soy.

 

To treat Moderate Acute Malnutrition

People who fall under the cut-off for moderate acute malnutrition (using Mid Upper Arm Circumference, Weight/Height ratio) need to receive an adapted diet that allows them to regain a normal nutritional status. The diet particularly needs to account for elevated nutrient and energy requirements.

A lipid-based nutritional supplement with a high vitamin and mineral content, such as Plumpy’Sup™, is well-adapted to the needs of moderate acute malnourished people. Results that can be achieved with Plumpy’Sup™ have shown to be superior to those attained with fortified blended flours.

With these caracteristics, home use is possible and the product is particularly well adapted to emergency contexts or to nutritional programs to prevent malnutrition.

 

Plumpy’Sup™ is not substitute for a varied and nutritious diet and for breastfeeding.

Immediate breastfeeding after birth, exclusive during the first 6 months and recommended for at least 24 months.

Main nutritional values

Plumpy’Sup™ formula: elements for 100 g*
Energy 537 kcal Iron 11.2 mg Vitamin B1 1 mg
Proteins 12.1 g Iodine 140 µg Vitamin B2 2.6 mg
Lipids 35 g Selenium 20 µg Vitamin B6 2 mg
Calcium 630 mg Manganese 1.4 mg Vitamin B12 2.7 µg
Phosphorus 600 mg Sodium < 180 mg Vitamin K 27 µg
Potassium 1000 mg Vitamin A 750 µg Biotin 60 µg
Magnesium 170 mg Vitamin D 15 µg Folic acid 428 µg DFE
Zinc 12 mg Vitamin E 16.7 mg Pantothenic acid 6.6 mg
Copper 1.4 mg Vitamin C 60 mg Niacin 17.5 mg

*The values given in this table are based on Nutriset's knowledge of the intrinsic nutrient content of the raw materials and their variability, as well as the variability of the process.

Recent study on the efficacy of RUSF compared to Corn-Soy Blend (CSB)

• Fabiansen C et al. "Effectiveness of food supplements in increasing fat-free tissue accretion in children with moderate acute malnutrition: A randomised 2 × 2 × 3 factorial trial in Burkina Faso." PLoS Med. 2017 Sep 11;14(9):e1002387. 

This study reveals that , in the treatment of moderate acute malnutrition in children 6-23 months of age:

  • RUSFs have a better impact on recovery rate than CSB
  • RUSFs have a better impact on weight gain than CSB
  • This superiority in terms of weight gain is only seen in children treated with RUSF containing soy isolate. In other words, according to this study, those receiving RUSF dehulled soy flour did not have a better weight gain than those receiving CSB containing dehulled soy flour.
  • Children treated with RUSF have a higher fat-free tissue gain than those treated with CSB. This gain in fat-free tissue is associated with better growth in children.

 

Studies carried out with the Supplementary'Plumpy® formula (ex Plumpy'Sup™)

• Karakochuk C et al. "Treatment of moderate acute malnutrition with ready-to-use supplementary food results in higher overall recovery rates compared with a corn-soya blend in children in southern Ethiopia: an operations research trial." Am J Clin Nutr. (2012); 96:911-6.

• Chang CY et al. "Children successfully treated for moderate acute malnutrition remain at risk for malnutrition and death in the subsequent year after recovery." J Nutr. (2013); 143:215-20.

• Ackatia-Armah RS. "Malian children with moderate acute malnutrition who are treated with lipid-based dietary supplements have greater weight gains and recovery rates than those treated with locally produced cereal-legume products: a community-based, cluster-randomized trial." Am J Clin Nutr. (2015).

 

Other studies carried out

• Stobaugh HC et al. "Including whey protein and whey permeate in ready-to-use supplementary food improves recovery rates in children with moderate acute malnutrition: a randomized, double-blind clinical trial." Am J Clin Nutr. 2016 Mar;103(3):926-33. 

• Wang RJ et al. "Investigation of food acceptability and feeding practices for lipid nutrient supplements and blended flours used to treat moderate malnutrition." J Nutr. Educ Behav. 2013 May-Jun;45(3):258-63. 

• Cohuet S et al. "Intra-household use and acceptability of Ready-to-Use-Supplementary-Foods distributed in Niger between July and December 2010." Appetite. 2012 Dec;59(3):698-705.

• Matilsky DK et al. "Supplementary feeding with fortified spreads results in higher recovery rates than with a corn/soy blend in moderately wasted children." J Nutr. (2009); 139:773-8.